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OMERO will still list your images in their datasets, with their thumbnails, annotations, etc. However, for anything that involves reading the raw pixels (iviewer, OMERO.figure), OMERO will not be able to read your data anymore. Look at the Fileset information to find the original name and location of the file to revert your changes back.

• Is it faster to import large images this way

What is faster is that the images are not uploaded to the server. However, if your images are large in X and Y (>3000), OMERO still needs to process subresolutions for each plane (that can increases rapidly when considering multiple channels, timepoints are Z-slices). For faster import, you have to generate the pyramidal resolutions and import the resulting images (remember to discard the previous image to not occupy twice the storage space). This can most easily be done for free with https://www.glencoesoftware.com/products/ngff-converter/   See Convert to ome.tiff wiki page (under construction)